Succinylated Triticum vulgaris (Wheat) Lectin (Succ WGA) - Pure

Succinylated Triticum vulgaris (Wheat) Lectin (Succ WGA) - Pure

Regular price $99.00 Sale
SKU# 30330042-1

Product Description

Succinylated wheat germ agglutinin (Succ-WGA) is isolated from wheat germ (Triticum vulgaris) and is a derivative from the native wheat germ agglutinin (WGA). It has a molecular weight of 36,000 and is an acidic protein with an isoelectric point of pH 4.0 +/- 0.2. It is dimeric at pH down to 5 with a dissociation that occurs at pH lower than 4.5. Succ-WGA agglutinates rabbit erythrocytes at a minimal concentration of about 2 µg/ml, and also agglutinates human erythrocytes of blood groups A, B, and O types. It has a carbohydrate specificity towards GlcNAc and elutes a concentration of chitin hydrolysate or GlcNAc with acid or salt.

The solubility of Succ-WGA is around 100 times higher than the unmodified lectin at neutral pH. Studies suggests that Succ-WGA does not bind to sialic acid residues, unlike WGA, but retains its specificity towards N-acetylglucosamine. Using conjugates of the native lectin and the succinylated form can provide a system to distinguish between sialylated glycoconjugates and those containing N-acetylglucosamine structures.

This product comes in a lyophilized form and is stored at -20°C. Calcium is required for binding.

Technical Specifications

Molecular Weight: 36 kDa
Synonyms: WGA
Shelf Life: 2 years
Storage Temperature: -20°C
Hazardous Shipping: Non-hazardous