Maackia amurensis Lectin (MAA/MAL I) - Pure

Maackia amurensis Lectin (MAA/MAL I) - Pure

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SKU# 21510007-1

Product Description

Leukoagglutinating lectin (MAL I) is isolated from Amur seeds, Maackia amurensis, and is a glycoprotein composed of 287 amino acid residues. This lectin has a molecular weight of 130,000 and is a dimer of two subunits. MAL I has an isoelectric point of pH 4.7 and a carbohydrate specificity for Galß4GlcNAc. This lectin elutes with the sugar lactose.

MAL I has non-specific blood group specificity and therefore agglutinates all types of human erythrocytes. MAL I requires three intact sugar units for binding and does not interact when ‚àö√º1,4-linkage is replaced with ‚àö√º1,3-linkage, nor when the ‚Äö√†√∂¢‚Äö√Ñ√∂‚àö√°Æº‚Äö√†√∂‚àö√¢‚Äö√Ñ√∂‚àö√ë‚Äö√†¬¥‚Äö√†√∂‚àö√¢®‚àö¬Æreducing sugar'‚àöœÄ of trisaccharide is reduced. Repeating sequence of N-acetyllactosamine is not required but does enhance the binding of MAL I to a series of glycolipids. Either N-acetyl or N-glycosyl groups may be substituted without reduction in binding.

This product comes in a lyophilized form and is stored at -20ºC. Reconstitute with sterile buffer. No metal ions are required for binding.

Technical Specifications

Molecular Weight: 130 kDa
Synonyms: MAA/MAL I
Shelf Life: 2 years
Storage Temperature: -20°C
Hazardous Shipping: Non-hazardous