Datura stramonium Lectin (DSA/DSL) - Pure
Regular price
$130.00
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SKU# 21510038-1
Product Description
Datura stramonium agglutinin or lectin (DSA/DSL) is purified by affinity chromatography. Seeds of Datura stramonium contain at least three different carbohydrate-binding proteins, and the most prominent lectin is a dimeric glycoprotein composed of two nonidentical subunits that contains 40% carbohydrate. It binds well to N-acetylglucosamine, oligomers, and branched pentasaccharide, including two N-acetylglucosamine disaccharides linked to mannose (?-1,6) and (?-1,2), which is known to be the most potent inhibitor of agglutination. DSL prefers binding to (GlcNAc)2-4 and elutes with the sugar chitin hydrolysate. DSL binds well in the acidic pH range and its affinity decreases above pH 8.0. This agglutinin has blood group A, B, and O specificity. Studies have shown that DSA can act as a biomarker for neoplastic urotherial cells.
Technical Specifications
Molecular Weight | : | 86 kDa |
Synonyms | : | DSA/DSL |
Appearance Form | : | White to off white |
Shelf Life | : | 2 years |
Storage Temperature | : | -20°C |
Hazardous Shipping | : | Non-hazardous |