Colchicine

Colchicine

$156.46 Sale
SKU# 40300104-1

Product Description

Antimitotic agent that disrupts microtubules by binding to tubulin and preventing its polymerization. Stimulates the intrinsic GTPase activity of tubulin. Induces apoptosis in several normal and tumor cell lines and activates the JNK/SAPK signaling pathway.

Synonyms: Acetamide, N-(5,6,7,9-tetrahydro-1,2,3,10-tetramethoxy-9-oxobenzo[a]heptalen-7-yl)-, (S)-;colchicine; 7-alpha-h-colchicine;7alpha-h-colchicine;acetamide, n-(5,6,7,9-tetrahydro-1,2,3,10-tetramethoxy-9-oxobenzo(alpha)hepta;len-7- yl)-; n-(5,6,7,9-tetrahydro-1,2,3,10-tetramethoxy-9-oxobenzo(a)heptalen-7-acetamide; (s)-yl); n-(5,6,7,9-tetrahydro-1,2,3,10-tetramethoxy-9-oxobenzo[a]heptalen-7-acetamide; (s)-yl); benzo(a)heptalen-9(5h)-one;7-acetamido-6,7-dihydro-1,2,3,10-tetramethoxy-benzo(a)heptalen-9(5h)-one;colchicin;colchicina;colchicine;colchineos;colchisol;colcin;colsaloid;condylon; n-(5,6,7,9-tetrahydro-1,2,3,10-tetramethoxy-9-oxobenzo[a]heptalen-7-yl)acetamid;e; n-acetyl trimethylcolchicinic acid methylether; nsc 757

Light Sensitive

  • Appearance: Yellow powder
  • Boiling Point: 726.03 °C at 760 mmHg (Predicted)
  • Density: 1.26 g/cm3 (Predicted)
  • IUPAC_Name: N-R03;[(7S)-R03;1,R03;2,R03;3,R03;10-R03;Tetramethoxy-R03;9-R03;oxo-R03;5,R03;6,R03;7,R03;9-R03;tetrahydrobenzoR03;[a]R03;heptalen-R03;7-R03;yl]R03;acetamide
  • Melting Point: 150-160 °C
  • RTECS Number: GH0700000

Technical Specifications

CAS#: 64-86-8
Molecular Weight: 399.44
Molecular Formula: C22H25NO6
Synonyms: (S)-N-(5,6,7,9-Tetrahydro-1,2,3,10-tetramethoxy-9-oxobenzo[a]heptalen-7-yl)-acetamide
Appearance Form: Powder
Appearance Color: White to yellow
Working Concentration: 0
Solubility: H2O: 45 mg/mL at 20°C
Soluble in alcohol and chloroform. Practically insoluble in petroleum ether and benzene
Shelf Life: 2 years
Storage Temperature: RT
Hazardous Shipping: Non-hazardous

Applications

References