Artocarpus integrifolia (Jacalin) Lectin (AIA) - Pure
Jacalin lectin (AIA) is isolated from jackfruit seeds (Artocarpus integrifolia) and purified by affinity chromatography. AIA is a tetrameric two-chain structure consisting of four identical protomers and a molecular weight of 66,000, with an isoelectric point of pH 7.8. The lectin has specificity for blood group types O (+SA) and T.
Jacalin is considered a galactose-specific lectin and elutes with galactose or melibiose. A post-translational proteolytic modification of Jacalin gives the lectin a novel carbohydrate-binding site involving the N terminus of the ?-chain. The protein’s structure explains it’s carbohydrate-binding specificity of T-antigen disaccharide Gal?1,3GalNAc. Potent inhibitors of jacalin include D-galactose, ?-Met-Gal and 2-deoxy-?-D-galactose.
This product comes in a lyophilized form and is stable for more than five years when stored below -20°C.
|Molecular Weight||:||66 kDa|
|Shelf Life||:||2 years|