Artocarpus integrifolia Lectin (AIA) - Pure
Regular price
$188.00
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SKU# 21510001-1
Product Description
Artocarpus integrifolia Lectin (AIA) is purified by affinity chromatography and is tetrameric two-chain structure consisting of four identical protomers with an isoelectric point of pH 7.8. The lectin has specificity for blood group types O (+SA) and T. Jacalin is considered a galactose-specific lectin and elutes with galactose or melibiose. A post-translational proteolytic modification of Jacalin gives the lectin a novel carbohydrate-binding site involving the N terminus of the α-chain. The protein's structure explains its carbohydrate-binding specificity of T-antigen disaccharide Galß1,3GalNAc. Potent inhibitors of jacalin include D-galactose, ß-Met-Gal and 2-deoxy-α-D-galactose. This product comes in a stable lyophilized form.
Specifications:
- Source: Artocarpus integrifolia (Jackfruit)
- Activity: Less than 0.5 ug /ml will agglutinate neuraminidase treated human erythrocytes.
- Carbohydrate Specificity: Galß1-3GalNAc
- Inhibitory Carbohydrate: Galactose or Melibiose
- Mitogenic Activity: Yes
- Divalent ions required: None
Storage and Stability:
Store frozen at -20°C in amber vials or covered with foil in appropriate aliquot sizes. Avoid freeze thaw cycles. Can be stored at 2-8°C for short term use.
Technical Specifications
| Molecular Weight | : | 66 kDa |
| Synonyms | : | AIA |
| Shelf Life | : | 2 years |
| Storage Temperature | : | -20°C |
| Hazardous Shipping | : | Non-hazardous |