Griffonia simplicifolia Lectin (GSL I+II) - Pure

Griffonia simplicifolia Lectin (GSL I+II) - Pure

Regular price $159.89 Sale
SKU# 21510005-1

Product Description

Griffonia simplicifolia lectin (GSL I+II) is isolated from a woody climbing shrub native to Africa and purified by affinity chromatography. It consists of both lectins GSL I+II, that a molecular weight of 114,000 and an isoelectric point between pH 5.0 to pH 6.5. This lectin has carbohydrate specificity for ?Gal and ?GalNAc, and elutes with galactose or N-acetylgalactosamine. GSL I+II shows specificity for blood group B greater than blood group A1.

This lectin interacts with pulmonary microvascular endothelial cells, but does not readily interact with pulmonary arterial endothelial cells. This binding pattern has been successfully utilized to enrich cell populations in vitro that possess functional behaviors characteristic of those seen in vivo.

This product comes in a lyophilized form and is stored at -20ºC. Calcium and manganese ions are required for binding.

Technical Specifications

Molecular Weight: 114 kDa
Synonyms: GSL I+II
Shelf Life: 2 years
Storage Temperature: -20°C
Hazardous Shipping: Non-hazardous

Applications

Glycobiology, Alveolar endothelium recognition

References