Amaranthus caudatus Lectin (ACL/ACA) - Pure
Amaranthus caudatus lectin or agglutinin (ACL/ACA) is isolated from tassel flower seeds. This lectin is present in seeds only and not in stems or in leaves. ACL is a dimer composed of two subunits and is homogeneous by SDS-PAGE, with a molecular weight between 60,000 - 70,000. Unlike most lectins, it binds best in mildly acidic conditions. Isoelectric focusing of the lectin resolves it into four bands with an isoelectric point between pH 6.7 and pH 7.7.
This lectin preferentially binds to oligosaccharides containing Gal?3GalNAc, with an eluting sugar of desialyzed fetuin. ACL tolerates sialic acid substitution at the 3 position of galactose in the ‚Äö√†√∂¢‚Äö√Ñ√∂‚àö√°Æº‚Äö√†√∂‚àö√¢‚Äö√Ñ√∂‚àö√ë‚Äö√†¬¥‚Äö√†√∂‚àö√¢®‚àö¬ÆT'‚àöœÄ antigen. It does not have specificity for blood groups but does have a higher affinity for type O erythrocytes over B and A.
This product comes in a lyophilized form and is stored below -20ºC. Reconstitute with sterile buffer or ddH2O. No metal ions are required for binding.