Maackia amurensis Lectin (MAA/MAL I) - Pure
Regular price
$123.02
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SKU# 21510007-1
Product Description
Leukoagglutinating lectin (MAL I) is isolated from Amur seeds, Maackia amurensis, and is a glycoprotein composed of 287 amino acid residues. This lectin has a molecular weight of 130,000 and is a dimer of two subunits. MAL I has an isoelectric point of pH 4.7 and a carbohydrate specificity for Galß4GlcNAc. This lectin elutes with the sugar lactose.
MAL I has non-specific blood group specificity and therefore agglutinates all types of human erythrocytes. MAL I requires three intact sugar units for binding and does not interact when ‚àö√º1,4-linkage is replaced with ‚àö√º1,3-linkage, nor when the ‚Äö√†√∂¢‚Äö√Ñ√∂‚àö√°Æº‚Äö√†√∂‚àö√¢‚Äö√Ñ√∂‚àö√ë‚Äö√†¬¥‚Äö√†√∂‚àö√¢®‚àö¬Æreducing sugar'‚àöœÄ of trisaccharide is reduced. Repeating sequence of N-acetyllactosamine is not required but does enhance the binding of MAL I to a series of glycolipids. Either N-acetyl or N-glycosyl groups may be substituted without reduction in binding.
This product comes in a lyophilized form and is stored at -20ºC. Reconstitute with sterile buffer. No metal ions are required for binding.
Technical Specifications
| Molecular Weight | : | 130 kDa |
| Synonyms | : | MAA/MAL I |
| Shelf Life | : | 2 years |
| Storage Temperature | : | -20°C |
| Hazardous Shipping | : | Non-hazardous |