Product Description Buffer-saturated phenol has a pH level of 7.6 and is suitable for phenol extraction of nucleic acid solutions. It consists of phenol that has been saturated with aqueous Tris-HCl buffer (pH = 8.0). It is free from interfering levels of heavy metals and antioxidants, including hypophosphorous acid. Mixtures that are extracted with the buffer denature proteins and are collected in the organic phase or at the interphase, while most nucleic acids remain in the aqueous phase. This buffer contains no preservatives.